David C Ware Selected Research

cyclen

7/2013	Cross-bridged cyclen or cyclam Co(III) complexes containing cytotoxic ligands as hypoxia-activated prodrugs.
8/2011	N-alkylated cyclen cobalt(III) complexes of 1-(chloromethyl)-3-(5,6,7-trimethoxyindol-2-ylcarbonyl)-2,3-dihydro-1H-pyrrolo[3,2-f]quinolin-5-ol DNA alkylating agent as hypoxia-activated prodrugs.
12/2010	Syntheses of 8-quinolinolatocobalt(III) complexes containing cyclen based auxiliary ligands as models for hypoxia-activated prodrugs.
9/2004	Optimization of the auxiliary ligand shell of Cobalt(III)(8-hydroxyquinoline) complexes as model hypoxia-selective radiation-activated prodrugs.

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David C Ware Research Topics

Disease

6	Hypoxia (Hypoxemia) 07/2013 - 09/2004
1	Neoplasms (Cancer) 09/2004

Drug/Important Bio-Agent (IBA)

5	ProdrugsIBA 07/2013 - 09/2004
4	cyclenIBA 07/2013 - 09/2004
4	LigandsIBA 07/2013 - 09/2004
4	Alkylating AgentsIBA 07/2013 - 09/2004
3	CobaltIBA 07/2013 - 06/2006
3	DNA (Deoxyribonucleic Acid)IBA 08/2011 - 09/2004
2	Cytotoxins (Cytolysins)IBA 11/2009 - 09/2004
1	cyclamIBA 07/2013
1	Oxygen (Dioxygen)IBA 07/2013
1	Coordination ComplexesIBA 11/2009
1	quinolineIBA 11/2009
1	azachloromethylbenzindolineIBA 06/2006
1	Oxyquinoline (8 Hydroxyquinoline)FDA Link 09/2004
1	EnzymesIBA 09/2004